In File, the player takes the role of young man named Pat, who is working for a powerful state security organization in an unspecified English-speaking country. His boss, a mysterious high-ranked agent named Cropp, tells him about a strictly classified project under the codename IBIS, which was intended as a counter-terror measure. Four young women have been apprehended under suspicious circumstances (amnesia following an accident, proximity to weapon research facility, etc.). Pat's task is to interrogate those women and to find out the truth about their activities.