The main character, Masashi Kozue, is a teacher who works at a certain school. He lives a fulfilling life surrounded by noisy yet cute students. That is until, by chance, his students find out that he is actually still a virgin, thus earning him the unfortunate nickname of "Virgin Sensei''. Teased and mocked about this day after day, Masashi begins to strongly desire to lose his virginity. Gradually, and perhaps unsurprisingly, he starts to see his students in a sexual way.